Failure, faith and $8 billion: How Lilly’s amyloid conviction brought it to the brink of Alzheimer’s approval

Twenty-nine years ago, Eli Lilly bought an old, ivy-covered brick house in Marktbreit, Germany.

The house was the childhood home of Alois Alzheimer, who had peered through his microscope and discovered suspicious looking plaques in samples of brains ravaged by dementia. Nearly a century later, in 1995, Lilly’s executives had…
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